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・ Posterior longitudinal ligament
・ Posterior median line
・ Posterior median sulcus
・ Posterior median sulcus of medulla oblongata
・ Posterior median sulcus of spinal cord
・ Posterior meningeal artery
・ Posterior meniscofemoral ligament
・ Posterior nasal apertures
・ Posterior nasal spine
・ Posterior nucleus of hypothalamus
・ Posterior parahippocampal gyrus
・ Posterior parietal cortex
・ Posterior perforated substance
・ Posterior pituitary
・ Posterior pole
Posterior polymorphous corneal dystrophy
・ Posterior predictive distribution
・ Posterior probability
・ Posterior proper fasciculus
・ Posterior rami syndrome
・ Posterior ramus of spinal nerve
・ Posterior reversible encephalopathy syndrome
・ Posterior sacrococcygeal ligament
・ Posterior sacroiliac ligament
・ Posterior scrotal arteries
・ Posterior scrotal branches
・ Posterior scrotal nerves
・ Posterior scrotal veins
・ Posterior segment of eyeball
・ Posterior septal branches of sphenopalatine artery


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Posterior polymorphous corneal dystrophy : ウィキペディア英語版
Posterior polymorphous corneal dystrophy

Posterior Polymorphous Corneal Dystrophy (PPCD; sometimes also ''Schlichting dystrophy'') is a type of corneal dystrophy, characterised by changes in Descemet's membrane and endothelial layer. Symptoms mainly consist of decreased vision due to corneal edema. In some cases they are present from birth, other patients are asymptomatic. Histopathological analysis shows that the cells of endothelium have some characteristics of epithelial cells and have become multilayered. The disease was first described in 1916 by Koeppe as ''keratitis bullosa interna''.
PPCD type 2 is linked to the mutations in COL8A2, and PPCD type 3 mutations in ZEB1 gene, but the underlying genetic disturbance in PPCD type 1 is unknown.
== Clinical features ==
Vacuoles are demonstrated in the posterior parts of the cornea. The vesicles are located on the endothelial surface. The corneal endothelium is normally a single layer of cells that lose their mitotic potential after development is complete. In posterior polymorphous corneal dystrophy, the endothelium is often multilayered and has several other characteristics of an epithelium, including the presence of desmosomes, tonofilaments, and microvilli. These abnormal cells retain their ability to divide and extend onto the trabecular meshwork to cause glaucoma in up to 40% of cases.〔(【引用サイトリンク】url=http://omim.org/entry/122000 )

抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)
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